In accordance with its mission to support high level research in Belgium, the University Foundation provides financial support towards the publication in high level international journals of scientific papers which report on research in Belgian research groups. Financial support may be granted to partially cover the costs due by the author for illustrations, for page charges and for article processing fees, and for linguuistic control.
What follows is a list of articles to which a subsidy was awarded by the University Foundation. The titles are ordered by year of publication and by title.
The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells
WANG, J. et al. (2015) The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells. Oncotarget vol. 6, n° 41, pp. 43992-44004.
Exosomes, extracellular nanovesicles secreted by various cell types, modulate the bone marrow (BM) microenvironment by regulating angiogenesis, cytokine release, immune response, inflammation, and metastasis. Interactions between bone marrow stromal cells (BMSCs) and multiple myeloma (MM) cells play crucial roles in MM development. We previously reported that BMSC-derived exosomes directly promote MM cell growth, whereas the other possible mechanisms for supporting MM progression by these exosomes are still not clear.
Merken R, Deboelpaep E, Teunen J, Saura S, Koedam N (2015) Wetland Suitability and Connectivity for Trans-Saharan Migratory Waterbirds. PLoS ONE 10(8): e0135445. doi:10.1371/journal.
To complete their life cycle waterbirds rely on patchily distributed and often ephemeral wetlands along their migration route in a vast unsuitable matrix. However, further loss and degradation of remaining wetland habitats might lead to a configuration and size of stopovers that is no longer sufficient to ensure long-term survival of waterbird populations.
LALOY, J. et al., (2014) Can TiC nanoparticles produce toxicity in oral administration to rats? Toxicology Reports, vol. 1, pp. 172-187
For decades, cognitive adaptation to response conflict has been considered to be the hallmark of cognitive control. Notwithstanding a vast amount of evidence ruling out lowlevel interpretations of these findings, disbelief still exists with regard to the underlying cause of the observed effects. Especially when considering cognitive adaptation to unconscious conflict, it is still a matter of debate whether repetitions of features between trials might explain this intriguing finding rather than the involvement of unconscious control.
In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma
MAES, K. et al. (2014) In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma, Oncotarget, 6(5), 3319-3334.
Histone deacetylase inhibitors (HDACi) and DNA methyltransferase inhibitors (DNMTi) are in early clinical development for multiple myeloma (MM) therapy. Despite all encouraging pre-clinical data, clinical activity of HDACi and DNMTi is mostly lacking. To optimize the trials, characterization of the in vivo response towards HDACi and DNMTi will be crucial. Therefore, we investigated the transcriptional response after in vivo treatment with the HDACi quisinostat or DNMTi decitabine using the murine 5T33MM model.
The Confusion of the Battlefield. A New Perspective on the Tapestries of the Battle of Pavia (c. 1525-1531)
PAREDES, C. (2014) The Confusion of the Battlefield. A New Perspective on the Tapestries of the Battle of Pavia (c. 1525-1531) RIHA Journal 0102 (28 December 2014)
This contribution is devoted to the tapestry cycle of the Battle of Pavia conserved at the Museo Capodimonte in Naples. Seven tapestries compose this prestigious tapestry set that commemorates the first military success of Charles V: the battle held in Pavia on 24 February 1525. Up to now the tapestries have been interpreted as independent panels representing different episodes of the battle. In this contribution we will show that the seven panels actually originated in one single design, which we rediscovered by assembling them in a different sequence.
VANDERELST D., SPEYBROECK N. (2013) An adjusted bed net coverage indicator with estimations for 23 African countries. Malaria Journal 12:457
Background: Many studies have assessed the level of bed net coverage in populations at risk of malaria infection. These revealed large variations in bed net use across countries, regions and social strata. Such studies are often aimed at identifying populations with low access to bed nets that should be prioritized in future interventions. However, often spatial differences in malaria endemicity are not taken into account.
Seasonal, Diurnal and Vertical Variation of Chlorophyll Fluorescence on Phyllostachys humilis in Ireland
VAN GOETHEM D, DE SMEDT S, VALCKE R, POTTERS G, SAMSON R (2013) Seasonal, Diurnal and Vertical Variation of Chlorophyll Fluorescence on Phyllostachys humilis in Ireland. PLoS ONE 8(8): e72145. Correction: PLoS ONE 8(11): 10.1371.
In recent years, temperate bamboo species have been introduced in Europe not only as an ornamental plant, but also as a new biomass crop. To measure adaptation stress of bamboo to the climate of Western Europe, chlorophyll fluorescence was measured on a diurnal and seasonal basis in Ballyboughal, Co. Dublin, Ireland. Measurements were attained on the leaves of each node of Phyllostachys humilis. The most frequently used parameter in chlorophyll fluorescence is the photosynthetic efficiency (Fv/Fm).
Tracking earthquake archaeological evidence in Late Minoan IIIB (~1300-1200 B.C.) Crete (Greece): A proof of concept
JUSSERET S., LANGOHR C., SINTUBIN M. (2013). Tracking earthquake archaeological evidence in Late Minoan IIIB (~1300-1200 B.C.) Crete (Greece): A proof of concept. Bulletin of the Seismological Society of America, 103, 3026-3043.
Late Minoan (LM) IIIB (∼1300–1200 B.C.) represents a crucial period in the history of Bronze Age Crete, heralding the transition to the Iron Age through a wave of site destruction and abandonment. According to the traditional view, earthquakes may have played a significant role in these events. A new archaeoseismological approach is proposed to test this hypothesis and to attribute destruction and abandonment to earthquakes. Potential earthquake archaeological effects (PEAEs) are defined and documented at LM IIIB sites.
Masked auditory thresholds in three species of birds, as measured by the auditory brainstem response (L)
NOIROT, I. C., BRITTAN-POWELL, E. F., & DOOLING, R. J. (2011). Masked auditory thresholds in three species of birds, as measured by the auditory brainstem response (L). Acoustical Society of America, 129, 6, 3445-3448.
Auditory brainstem responses (ABRs) were recorded in adult budgerigars, canaries, and zebra finches in quiet and in three levels of white noise for tone stimuli between 1 and 4 kHz. Similar to behavioral results, masked ABR thresholds increased linearly with increasing noise levels. When the three species are considered together, ABR-derived CRs were higher than behavioral CRs by 18–23 dB between 2 and 4 kHz and by about 30 dB at 1 kHz.
FELTEN, A., SUAREZ-MARTINEZ, I., KE, X., VAN TENDELOO, G., GHIJSEN, J., PIREAUX, J-J., DRUBE, W., BITTENCOURT, C., & EWELS, C. (2009). The role of oxygen at the interface between titanium and carbon nanotubes. Chemphyschem : A European Journal of Chemical Physics and Physical Chemistry, vol 10, issue 11, 1799-1804.
We study the interface between carbon nanotubes (CNTs) and surface-deposited titanium using electron microscopy and photoemission spectroscopy, supported by density functional calculations. Charge transfer from the Ti atoms to the nanotube and carbide formation is observed at the interface which indicates strong interaction. Nevertheless, the presence of oxygen between the Ti and the CNTs significantly weakens the Ti–CNT interaction. Ti atoms at the surface will preferentially bond to oxygenated sites.