Articles Scientifiques

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Articles scientifiques, subventionnés par la Fondation Universitaire.

Ce qui suit est une liste d'articles scientifiques auxquelles une subvention a été accordée par la Fondation Universitaire. Les articles sont triés par année de publication et par titre.

Youssef Sanhadji El Haddar, Sibel Cetik, Babak Bahrami, and Ramin Atash

El HaddarY.S., Cetik S., Bahrami, B., and Atash R. (2016) A Comparative Study of Microleakage on Dental Surfaces Bonded with Three Self-Etch Adhesive Systems Treated with the Er:YAG Laser and Bur, BioMed Research International, vol. 2016, Article ID 2509757, 6 pages, doi:10.1155/2016/2509757

This study sought to compare the microleakage of three adhesive systems in the context of Erbium-YAG laser and diamond bur cavity procedures. Cavities were restored with composite resin.

Benoit Van Driessche et al.

Van Driessche, B. et al. (2016) Characterization of new RNA polymerase III and RNA polymerase II transcriptional promoters in the Bovine Leukemia Virus genome. Sci. Rep. 6, 31125.

Bovine leukemia virus latency is a viral strategy used to escape from the host immune system and contribute to tumor development. However, a highly expressed BLV micro-RNA cluster has been reported, suggesting that the BLV silencing is not complete. Here, we demonstrate the in vivo recruitment of RNA polymerase III to the BLV miRNA cluster both in BLV-latently infected cell lines and in ovine BLV-infected primary cells, through a canonical type 2 RNAPIII promoter.

Demonceau M. et al.

Demonceau, M. et al. (2016) Effects of 12 weeks of aerobic or strength training in addition to standard care in Parkinson's disease.  European Journal of physical and rehabilitation medicine

BACKGROUND: Physical exercises in addition to standard care (SC) in patients with Parkinson’s disease (PD) are now common practice in many care units. However, exercises can cover a wide range of interventions, and the specific effects of different interventions still deserve to be further investigated.
AIM: To compare the effects of 12 weeks of two different types of physical exercises with SC in patients suffering from PD.
DESIGN: Pseudo-randomized controlled trial.
SETTING: University laboratory for outcomes, University Hospital Centre for interventions.

Susanne Lub, Anke Maes, Ken Maes, Kim De Veirman, Elke De Bruyne, Eline Menu, Karel Fostier, Alboukadel Kassambara, Jérôme Moreaux, Dirk Hose, Xavier Leleu, Randall W. King, Karin Vanderkerken, Els Van Valckenborgh

Lub, S. et al. (2016) Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells, Oncotarget, vol. 7, n° 4.

The anaphase promoting complex/cyclosome (APC/C) is an ubiquitin ligase involved in cell cycle. During the metaphase-anaphase transition the APC/C is activated by Cdc20. The aim of this study is to elucidate the importance and therapeutic potential of APC/C and its co-activator Cdc20 in multiple myeloma (MM). Gene expression analysis revealed that Cdc20 was expressed at higher levels in gene expression-based high-risk MM patients. Moreover, high Cdc20 expression correlated with poor prognosis.

Viviana Otero, Katrien Quisthoudt, Nico Koedam and Farid Dahdouh-Guebas

Otero, V.; Quisthoudt, K.; Koedam, N.; Dahdouh-Guebas, F. (2016) Mangroves at Their Limits: Detection and Area Estimation of Mangroves along the Sahara Desert CoastRemote Sensing, 8, 512.

The northernmost and most arid mangrove ecosystem ofWest Africa is found in Mauritania, in the Parc National du Banc d’Arguin (PNBA). The existing global and regional maps of Mauritania’s mangroves have little detail, and available estimates of the mangrove area differ among studies. We assessed the use of automated Remote Sensing classification techniques to calculate the extent and map the distribution of the mangrove patches located at Cap Timiris, PNBA, using QuickBird and GeoEye imagery.

Jan ORBIE et al.

Orbie, J. et al. (2016) Promoting sustainable development or legitimising free trade? Civil society mechanisms in EU trade agreementsThird World Thematics,  vol 1, 4, 526-546.

Lechthaler Silvia, Robert Elisabeth M. R., Tonné Nathalie, Prusova Alena, Gerkema Edo, Van As Henk, Koedam Nico, Windt Carel W.

Lechthaler, S. et al. (2016) Rhizophoraceae mangrove saplings use hypocotyl and leaf water storage capacity to cope with soil water salinity changesFrontiers in Plant Science, 2016, issue 00895, 

Some of the most striking features of Rhizophoraceae mangrove saplings are their voluminous cylinder-shaped hypocotyls and thickened leaves. The hypocotyls are known to serve as floats during seed dispersal (hydrochory) and store nutrients that allow the seedling to root and settle. In this study we investigate to what degree the hypocotyls and leaves can serve as water reservoirs once seedlings have settled, helping the plant to buffer the rapid water potential changes that are typical for the mangrove environment.

Arimatéa C. Ximenes, Eduardo Eiji Maeda, Gustavo Felipe Balué Arcoverde and Farid Dahdouh-Guebas

Ximenes A.C. et al. (2016) Spatial Assessment of the Bioclimatic and Environmental Factors Driving Mangrove Tree Species’ Distribution along the Brazilian Coastline. Remote Sensing 2016, 8(6), 451; doi:10.3390/rs8060451

Brazil has one of the largest mangrove surfaces worldwide. Due to a wide latitudinal distribution, Brazilian mangroves can be found within a large range of environmental conditions. However, little attention has been given to the description of environmental variables driving the distribution of mangrove species in Brazil. In this study, we present a novel and unprecedented description of environmental conditions for all mangroves along the Brazilian coast focusing on species limits.

S De Groef, D Renmans, Y Cai, G Leuckx, S Roels, W Staels, G Gradwohl, L Baeyens, Y Heremans, GA Martens, N De Leu, M Sojoodi, M Van de Casteele and H Heimberg

De Groef S. et al. (2016) STAT3 modulates β-cell cycling in injured mouse pancreas and protects against DNA damage. Cell Death and Disease 7, e2272.

Partial pancreatic duct ligation (PDL) of mouse pancreas induces a doubling of the β-cell mass mainly through proliferation of preexisting and newly formed β-cells. The molecular mechanism governing this process is still largely unknown. Given the inflammatory nature of PDL and inflammation-induced signaling via the signal transducer and activator of transcription 3 (STAT3), the activation and the role of STAT3 in PDL-induced β-cell proliferation were investigated.

Dominique Engel

Engel, D. (2016) Subcellular Patch-clamp Recordings from the Somatodendritic Domain of Nigral Dopamine Neurons. J. Vis. Exp. (117), e54601, doi:10.3791/54601.

Dendrites of dopaminergic neurons receive and convey synaptic input, support action potential back-propagation and neurotransmitter release. Understanding these fundamental functions will shed light on the information transfer in these neurons. Dendritic patch-clamp recordings provide the possibility to directly examine the electrical properties of dendrites and underlying voltage-gated ion channels. However, these fine structures are not easily accessible to patch pipettes because of their small diameter.

C.A. MIDDLETON, C. THOMAS, A. DE WIT and J.-L. TISON

C.A. MIDDLETON, C. THOMAS, A. DE WIT and J.-L. TISON, Visualizing brine channel development and convective processes during artificial sea-ice growth using Schlieren optical methods, Journal of Glaciology, vol 62, Issue 231, Feb. 2016, pp. 1 - 17

Two non-invasive optical Schlieren methods have been adapted to visualize brine channel development and convective processes in experimentally grown sea ice obtained when a NaCl aqueous solution is cooled from above in a quasi-two-dimensional Hele–Shaw cell. The two different visualization methods, i.e. traditional and synthetic Schlieren optical imaging, produce high spatial resolution images of transport processes during ice growth, without any external perturbation.

Alexandre Heeren, Chris Baeken, Marie-Anne Vanderhasselt, Pierre Philippot, Rudi de Raedt

Heeren A, Baeken C, Vanderhasselt M-A, Philippot P, de Raedt R (2015) Impact of Anodal and Cathodal Transcranial Direct Current Stimulation over the Left Dorsolateral Prefrontal Cortex during Attention Bias Modification: An Eye-Tracking StudyPLOS ONE 10(4): e0124182. doi: 10.1371/journal.pone.0124182

People with anxiety disorders show an attentional bias for threat (AB), and Attention Bias Modification (ABM) procedures have been found to reduce this bias. However, the underlying processes accounting for this effect remain poorly understood. One explanation suggests that ABM requires the modification of attention control, driven by the recruitment of the dorsolateral prefrontal cortex (DLPFC). In the present double-blind study, we examined whether modifying left DLPFC activation influences the effect of ABM on AB.

Elke Van Lierde, Kobe Desender, Eva Van den Bussche

Van Lierde, E., Desender, K. & Van den Bussche, E. (2015) Is conflict adaptation triggered by feature repetitions? An unexpected finding. Frontiers in Psychology, vol. 5, number 01358

For decades, cognitive adaptation to response conflict has been considered to be the hallmark of cognitive control. Notwithstanding a vast amount of evidence ruling out lowlevel interpretations of these findings, disbelief still exists with regard to the underlying cause of the observed effects. Especially when considering cognitive adaptation to unconscious conflict, it is still a matter of debate whether repetitions of features between trials might explain this intriguing finding rather than the involvement of unconscious control.

Andrei Turtoi et al.

TURTOI, A. et al. (2015) Organized proteomic heterogeneity in colorectal cancer liver metastases and implications for therapiesHepatology, vol 59, issue 3, pp. 924–934.

Tumor heterogeneity is a major obstacle for developing effective anticancer treatments. Recent studies have pointed to large stochastic genetic heterogeneity within cancer lesions, where no pattern seems to exist that would enable a more structured targeted therapy approach.

BELLEFLAMME, A., FETTWEIS, X. & ERPICUM, M.

BELLEFLAMME, A., FETTWEIS, X. & ERPICUM, M. (2015)  Recent summer Arctic atmospheric circulation anomalies in a historical perspectiveThe Cryosphere, 9, 53–64.

A significant increase in the summertime occurrence of a high pressure area over the Beaufort Sea, the Canadian Arctic Archipelago, and Greenland has been observed since the beginning of the 2000s, and particularly between 2007 and 2012. These circulation anomalies are likely partly responsible for the enhanced Greenland ice sheet melt as well as the Arctic sea ice loss observed since 2007. Therefore, it is interesting to analyse whether similar conditions might have happened since the late 19th century over the Arctic region.

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